4 Patients Randomized. $1,250 Per Randomized Patient.
A Sanofi-sponsored Acne study site reached its randomization target through a compliant, targeted campaign, underpinned by a contractual commitment to outcomes, not activity.
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Patients Randomized
$5,000
Campaign Investment
$1,250
Cost Per Randomized Patient
When the Existing Patient Pool Is Not Enough
Clinical research sites running multiple active protocols face a resource allocation problem that compounds over time. Coordinators are stretched across studies. Referral networks that served one indication may not serve the next.
When a Sanofi-sponsored Acne study required enrollment beyond what the site's organic pipeline could support, the site faced a decision common to high-performing sites that still miss timelines: where do the additional patients come from, and who bears the cost if they don't arrive. In-house digital outreach exceeded what the site team could manage alongside active study operations. External vendors presented the same fundamental risk: spend first, results uncertain.
Four additional randomized patients were needed. The protocol timeline was defined. The site required a commitment, not a projection.
Feasibility Evaluation. IRB-Compliant Campaign. Screened Referrals Delivered to Site.
Feasibility confirmed four randomizable Acne patients could be reached through a $5,000 campaign envelope. Clinical Enroll built an IRB-compliant campaign targeted to the condition-specific patient profile, with pre-screened referrals delivered to the site's coordination team. The site's $5,000 investment was tied to a defined outcome.
4 Randomized Patients. $1,250 Per Patient. Protocol on Track.
The campaign delivered 4 randomized patients against a $5,000 investment, a cost per randomized patient of $1,250.
Per-patient site fees in Phase II-III studies typically range from $3,000 to $15,000 per randomized patient. At an estimated $3,000 to $15,000 per-patient site fee, 4 randomized patients represents a potential $12,000 to $60,000 in patient revenue against a $5,000 campaign investment.
The contractual randomization commitment meant the site team could plan around a defined outcome. Enrollment variance, one of the primary drivers of timeline slippage and sponsor friction, was transferred to Clinical Enroll before the campaign launched.
POTENTIAL ROI
$5,000
Campaign investment
$3k-$15k
Per-patient site fee range
$12k-$60k
Potential patient revenue
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All campaigns developed for IRB review and deployed in accordance with FDA guidance on clinical trial advertising.